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Seahorse Bioscience Receives Poster Award from The European Association for the Study of Obesity

Mechanism of Action of Metformin on Insulin Sensitization Poster Wins One of Three Prizes

N. Billerica, MA - Seahorse Bioscience, Inc., leaders in real-time measurement of cellular bioenergetics announced today the receipt of The European Association for the Study of Obesity (EASO) poster award at the 16th European Congress on Obesity (ECO 2008) May 14-17, 2008 in Geneva, Switzerland.

The poster, Mechanism of Action of Metformin on Insulin Sensitization: Selective Fatty Acid Oxidation (FAO) over Glucose Oxidation via Inhibition of Complex I and Activation of AMP-activated protein kinase in C2C12 myocytes presented by author Dr. Min Wu of Seahorse Bioscience, was one of three posters to win the prestigious 2008 EASO Poster Prize. Poster Prize winners have already been listed on the EASO website (www.easoobesity.org) and will be highlighted in the Association's next e-newsletter.

"We are very pleased that EASO recognized our work on cellular mechanism of action of metformin," said David Ferrick, Vice President of Biology. "It is the bioenergetic analysis of fuel substrate selections that revealed the mechanism of action in different cell types, an analysis with the potential to be very powerful in the understanding and treatment of many other age-related diseases."

"It is unusual for an instrument manufacturer to be recognized for scientific contribution but Seahorse XF technology enables novel discoveries by bringing to light the importance of energy producing pathways of the cell," said Steven Chomicz, Vice President of Sales and Marketing for Seahorse Bioscience. "Dr. Wu used the features of the XF24 extracellular flux analyzer to perform an eloquent experiment which revealed metformin's, heretofore, unknown mechanism of action. This potential for award winning discoveries is why Seahorse XF technology is used by leading bioenergetic labs worldwide."

About Seahorse Bioscience

Seahorse XF instruments have become the new standard in cellular bioenergetic measurements. Over 450 scientists worldwide are advancing their research in understanding the role of cellular bioenergetics in Aging, Cancer, Cardiovascular, Cell Physiology, Toxicology & Hepatobiology, Immunology, Infectious Diseases, Mitochondrial Diseases, Model Organisms, Neurodegeneration, Obesity, Diabetes, & Metabolic Disorders, Screening, and Translational Medicine. Founded in 2001, Seahorse is headquartered in Billerica, MA.